The main difference between you and your best friend is ...

I don't really have a 'best friend', bit old for that

Intelligence, education, religious beliefs and interests

She is more interested in art and I in literature.

I have some element of culture

Um, our height.
No, but she's way into arts as far as..theater and stuff like that..Whereas I more prefer music. We both like hands on artsy stuff, just she's better at it.

General outlook on life

boobs

I attempt systematic order of everything I do, while she does most everything by spontaneous intuition.

she's back in the US and I'm not.

I have several friends, one of them I've known almost 60 years, most 45 years. We all generally think alike. I have no male friends.

2 and 3: we have different interests but other commonalities

She's much less likely to go spouting off about something without having thought about it first. She thinks and then speaks. I speak and then think. I think her method is better.

One of the reasons we're best friends is because of how alike we are.

The main difference, I suppose, is that she has no ties.

I'm anal about handling my money, and he is very ... not.

There's so much! Our only similarity is that we both like to laugh and have laughed together for 25 years now.

The main difference is about 1800 miles.

1- Our gender is different
2- Our parents are different
3- We are different human beings

She's a year older, she's taller, she's weirder... But one thing we do have in common is that we love each other the way we are.

The main difference between us is I'm not imaginary.

Hm.

I have straight hair and his is curly?

I'm a little sloppy and he is tidy?

None of the differences I come up with seem like "main" differences.

Maybe it's our parenting ideas. I was raised in a pretty lenient and extremely loving home and he was raised in a very structured, sometimes violent home (I think of his childhood as violent - he doesn't). My parenting tends to be more like how I was raised and his seems to involve far more rules and verbal correcting of the child (i.e. don't sit so close to the TV, don't chew with your mouth open, sit up straight, etc.). I think it gives us a really well rounded parenting method -- he catches what I miss and I catch what he misses.

my best friend is invisible. I don't have any friends.

The difference between me and my best friend we are alike in so many ways me and her same blood and everything

Your a turtle and not even human that is the difference

3 (since she is my sister....)

I'm a man and he's a cat